what, Creatine?! LOL
The people who make these supplements usually know molecular biology, biochemistry, and physiology very well--creatine was brilliant because it really did show an apparent increase in muscle mass in a visible amount of time, but now that it's well know that that increase in mass is your muscles becoming engorged with water I have no idea why people keep taking it.
Yes, studies keep coming out that say it works, and then others say that it doesn't--but if you look at the money trail for the ones that say it works it leads almost unequivocally back to the supplement companies. that's reason enough for me to not trust their authenticity.
And still too many people go based on their "feelings" saying they definitely feel the difference it makes so they don't care what studies say.
Once again, your body makes its own creatine--I don't see how fucking with that is conducive to making yourself healthier (and what do you know, it's not).